apalutamide will minimize the level or impact of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of apalutamide, a strong CYP3A4 inducer, with medicines that happen to be CYP3A4 substrates can result in decrease publicity to these drugs.bremelanotide will decrease the extent or resul… Read More